ASYMMETRIC REACTIONS.1. ASYMMETRIC SYNTHESIS OF METHYL α-PHENYLPROPIONATE BY MEANS OF OPTICALLY ACTIVE POLYMERS
نویسندگان
چکیده
منابع مشابه
Organocatalytic synthesis of optically active β-branched α-amino esters via asymmetric biomimetic transamination.
This paper describes an efficient asymmetric biomimetic transamination of α-keto esters with a quinine-derived chiral base as the catalyst, giving a variety of β-branched α-amino esters in 50-96% yield and 87-95% ee.
متن کاملSynthesis of quaternary α-methyl α-amino acids by asymmetric alkylation of pseudoephenamine alaninamide pivaldimine.
The utility of pseudoephenamine as a chiral auxiliary for the alkylative construction of quaternary α-methyl α-amino acids is demonstrated. The method is notable for the high diastereoselectivities of the alkylation reactions, for its versatility with respect to electrophilic substrate partners, and for its mild hydrolysis conditions, which provide α-amino acids without salt contaminants. Alter...
متن کاملSynthesis of optically active dihydropyrans from asymmetric [4 + 2] cycloaddition of β,γ-unsaturated α-ketoesters with allenic esters.
β-Isocupreidine (β-ICD) catalyzed asymmetric [4 + 2] cycloaddition of β,γ-unsaturated α-ketoesters with allenic esters afforded ester-substituted functionalized dihydropyran derivatives in high yields along with high enantioselectivities under mild conditions.
متن کاملUltrahigh responsivity of optically active, semicondUcting asymmetric nanochannel diodes
LLE Review, Volume 143 167 Introduction Room-temperature nanodevices based on quantum confinement and/or ballistic nonlinearities are intrinsic nanostructures, not simply scaled-down conventional circuitry, and are gaining wide-spread research attention. Among the nanodevices, one of the most popular is the asymmetric nanochannel diode (ANCD), also referred to as a self-switching diode (SSD), f...
متن کاملAsymmetric synthesis of optically active methyl-2-benzamido-methyl-3-hydroxy-butyrate by robust short-chain alcohol dehydrogenases from Burkholderia gladioli.
Three short-chain alcohol dehydrogenases from Burkholderia gladioli were discovered for their great potential in the dynamic kinetic asymmetric transformation of methyl 2-benzamido-methyl-3-oxobutanoate, and their screening against varied organic solvents and substrates. This is the first report of recombinant enzymes capable of achieving this reaction with the highest enantio- and diastereo-se...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemistry Letters
سال: 1974
ISSN: 0366-7022,1348-0715
DOI: 10.1246/cl.1974.585